| Acronym | Meaning |
| CASA | Castillo de San Marcos National Monument (US National Park Service) |
| CASA | Centro de Acción Social (Guatemala political party) |
| CASA | Children & Adolescent Services Association |
| CASA | Civil Aviation Safety Authority (Australia) |
| CASA | Civilian Aide to the Secretary of the Army |
| CASA | Community Alternative Systems Agency (New York) |
| CASA | Computer Aided Situation Awareness |
| CASA | Construcciones Aeronauticas Sociedad Aónima (Spanish aerospace company and member of Airbus Industrie) |
| CASA | Coordinator for Army Security Assistance |
| CASA | Corporacion de Abastecimiento y Servicios Agricolas (Spanish, Venezuela) |
| CASA | Court Appointed Special Advocate |
| CASA | Court Appointed Special Advocate Program (various locations) |
| CASA | Court Appointed Special Advocates |