| Acronym | Meaning |
| MDM | Mailgram (US Navy) |
| MDM | Manpower Determination Model |
| MDM | Medium-Depth Mine |
| MDM | Mid-Day Meal (India) |
| MDM | Mobile Depot Maintenance |
| MDM | Mobility Diagnostic Module |
| MDM | Modern Day Marine (Quantico Marine military exhibition) |
| MDM | Modular Digital Multitracks |
| MDM | Monitor Drive Module |
| MDM | Movement for Department Status Mayotte (Mayotte) |
| MDM | Multipurpose Demilitarization Machine |