| Acronym | Meaning |
| OD | Off-Duty |
| OD | Office of Disability (Social Security) |
| OD | Office of the Director (NIH) |
| OD | Officer of the Day |
| OD | Official Declaration |
| OD | On Demand |
| OD | Open Detonation (outdoor munitions disposal regulation) |
| OD | Operating Division |
| OD | Operations Directive |
| OD | Operations Division |
| OD | Orbit Determination |
| OD | Orde Dienst (Dutch: Order of Service) |
| OD | Orderly Duty |
| OD | Ordinary Seaman (Canadian Navy) |
| OD | Ordnance |
| OD | Ordnance Data |
| OD | Ordnance Documentation |
| OD | Organizational Development |
| OD | Outside Dose (radiation exposure) |