| Acronym | Meaning |
| RLC | Radio Link Control |
| RLC | Range Light Controller (Coast Guard) |
| RLC | Regional Loan Center |
| RLC | Reliable Leasing Company (Midland, Michigan) |
| RLC | Report Landing Completed |
| RLC | Research Leadership Council (US FDA) |
| RLC | Royal Logistic Corps (UK armed forces) |
| RLC | Ruggedized Laptop Computer |
| RLC | Rural Limited Commercial (zoning) |