| Acronym | Meaning |
| MOE | MAD (Magnetic Anomoly Detection) Operational Effectiveness |
| MOE | Maintenance and Operating Expenses (various organizations) |
| MOE | Maintenance of Effort |
| MOE | Maintenance Organization Exposition (Canada) |
| MOE | Management Operating Environment |
| MOE | Material Obligation Established |
| MOE | Means of Escape |
| MOE | Measure Of Effectiveness |
| MOE | Measure of Evaluation (source selection) |
| MOE | Method of Entry |
| MOE | Method Of Evaluation |
| MOE | Minimum Operable Equipment |
| MOE | Minister of Economy (various locations) |
| MOE | Ministry of Education |
| MOE | Ministry of Energy (various nations) |
| MOE | Ministry Of Environment |
| MOE | Model of Excellence (various organizations) |