| Acronym | Meaning |
| ICS | Import Credit Scheme (Australian government) |
| ICS | In Country Support |
| ICS | Incident Command System |
| ICS | Indian Civil Service (now called IAS, Indian Administrative Services) |
| ICS | Industrial Control System (various organizations) |
| ICS | Informal Competitive Solicitation (Iowa) |
| ICS | Information and Communications Services |
| ICS | Inspection and Consumer Services (Colorado) |
| ICS | Instrument Control System |
| ICS | Instrumentation and Communications Subsystem |
| ICS | Integrated Cargo System (Australia) |
| ICS | Integrated Command/Combat System |
| ICS | Integration Control Sequencer |
| ICS | Intelligence and Security Committee (UK) |
| ICS | Intelligence Community Staff |
| ICS | Inter-Orbit Communication System (NASA) |
| ICS | Intercockpit Communication System |
| ICS | Intercom System |
| ICS | Intercommunication Control Set |
| ICS | Intercommunication Control System |
| ICS | Intercommunications System |
| ICS | Interdepartmental Committee on Security (various locations) |
| ICS | Interface Control Section |
| ICS | Interface Control Specification |
| ICS | Interferometer Control Subsystem |
| ICS | Interim Contractor Support |
| ICS | Intermittent Control Strategy |
| ICS | Intermittent Control System (environment) |
| ICS | Internal Calibrations System |
| ICS | Internal Controls Service |
| ICS | Internal Countermeasures System (Tactical Electronic Warfare Systems) |
| ICS | International Chamber of Shipping |
| ICS | International Computing Systems, Inc. |
| ICS | Interoperability Compliance Statement |
| ICS | Interpretive Computer Simulation |
| ICS | Interrupt Control Stack |
| ICS | Inventory Control System |
| ICS | ISDN Compatible Station |