| Acronym | Meaning |
| MOB | Mobilization/Mobilize/Mobility |
| MOB | Main Office Box (US Postal Service) |
| MOB | Main Operating Base |
| MOB | Main Operations Base (US DoD) |
| MOB | Management Operation Bridge |
| MOB | Management Oversight Board |
| MOB | Maritime Order of Battle |
| MOB | Medical Oncology Branch (National Cancer Institute) |
| MOB | Memorandum of Bailment |
| MOB | Missile Order of Battle |
| MOB | Mobile Off-shore Base |
| MOB | Mobility |
| MOB | Money Order Branch (various nations) |