| Acronym | Meaning |
| SDS | Scheme Development Standards (UK) |
| SDS | Scholarships for Disadvantaged Students (US HRSA) |
| SDS | Science Data Store |
| SDS | Self Defense System |
| SDS | Senior Drill Sergeant |
| SDS | Service Delivery Summary (Department of Defense Contracts) |
| SDS | SHF DAMA Standard |
| SDS | Shipboard Data System (US Navy) |
| SDS | SIGINT Data Server |
| SDS | Simulated Distressed Submarine |
| SDS | Site & Date Schedule |
| SDS | Site Data System (US Department of Energy) |
| SDS | Skills Development Services |
| SDS | Slovenska Demokratska Stranka (Slovenian Democratic Party) |
| SDS | Socijaldemokratska Stranka Slovenije (Social Democratic Party of Slovenia) |
| SDS | Software Development Specification |
| SDS | Sorbent Decontamination System |
| SDS | Space Defense System |
| SDS | Srpska Demokratska Stranka (Serb Democratic Party, Bosnia and Herzegovina) |
| SDS | Staff Development Section (various organizations) |
| SDS | Staff Development Summary |
| SDS | Standard Depot System |
| SDS | State Department of Statistics (various organizations) |
| SDS | Stored Data Smooth |
| SDS | Strategic Data System |
| SDS | Strategic Defense System |
| SDS | Strategic Deployment Stocks |
| SDS | Structured Design System |
| SDS | Submission Domain Standards |
| SDS | Subsurface Disposal System (various locations) |
| SDS | Successful Delivery Skills (UK) |
| SDS | Superior Decontamination System |
| SDS | Supply Depot System |
| SDS | Surveillance Direction System |
| SDS | Sustainable Development Strategy |
| SDS | Switched Data Service (FTS2000) |
| SDS | System Description Section |
| SDS | Szociáldemokrata Unió (Latvian: Social Democratic Union) |